F8257
Sigma
Flunarizine dihydrochloride
≥98% (TLC)
| Synonym: | 1-[Bis(4-fluorophenyl)methyl]-4-(3-phenyl-2-propenyl)piperazine dihydrochloride |
| CAS Number: | 30484-77-6 |
| Linear Formula: | C26H26F2N2 · 2HCl |
| Molecular Weight: | 477.42 |
| Beilstein Registry Number: | 4284243 |
| EC Number: | 250-216-6 |
| MDL number: | MFCD00058198 |
| PubChem Substance ID: | 24277835 |
Description
| Biochem/physiol Actions | Blocks T-type Ca2+/Na+ channels; inhibits K+-induced catecholamine release from chromaffin cells |
Properties
| assay | ≥98% (TLC) |
| storage temp. | 2-8°C |
Safety
| Personal Protective Equipment | dust mask type N95 (US), Eyeshields, Gloves |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| WGK Germany | 3 |
| RTECS | TK9187000 |
References
| reference | Terland, O., Flatmark, T. Neuropharmacology 38, 879, (1999) |
| Novalbos, J. Eur. J. Pharmacol. 366, 309, (1999) | |
| Ayajiki, K. Eur. J. Pharmacol. 329, 49, (1997) | |
| Merck | Merck 13,4170 |






