F8257

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F8257

Sigma

 

Flunarizine dihydrochloride

≥98% (TLC)

Synonym:1-[Bis(4-fluorophenyl)methyl]-4-(3-phenyl-2-propenyl)piperazine dihydrochloride
CAS Number:30484-77-6
Linear Formula:C26H26F2N2 · 2HCl
Molecular Weight:477.42
Beilstein Registry Number:4284243
EC Number:250-216-6
MDL number:MFCD00058198
PubChem Substance ID:24277835

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Reviews

Description

Biochem/physiol ActionsBlocks T-type Ca2+/Na+ channels; inhibits K+-induced catecholamine release from chromaffin cells

Properties

assay≥98% (TLC)
storage temp.2-8°C

Safety

Personal Protective Equipmentdust mask type N95 (US), Eyeshields, Gloves
Hazard CodesXn
Risk Statements22
WGK Germany3
RTECSTK9187000

References

referenceTerland, O., Flatmark, T. Neuropharmacology 38, 879, (1999)
 Novalbos, J. Eur. J. Pharmacol. 366, 309, (1999)
 Ayajiki, K. Eur. J. Pharmacol. 329, 49, (1997)
MerckMerck 13,4170